Purpose: Tissue equivalent materials have been widely used in medical imaging phantom. For radiologic image simulation, imaging characteristics and physical properties of phantom should be similar to real tissue they replicate. The mechanical properties of materials have been reported. However, medical imaging properties of materials, that are essential for phantom production, are not provided by the manufacturer. This work would be studied in detail the X-ray imaging properties of a selected number of tissue equivalent materials.
Methods: A variety of tissue equivalent materials were evaluated included several formulations of polylactic acid (PLA), acrylonitrile butadience styrene (ABS), light curing resin (LCR), epoxide resign, polyethylene (PE), silica gel and hydrogel (n = 9). All of these materials were fabricated using instructions of manufacturer recommended. X-ray attenuation coefficient (μ) was tested on a digital radiography (CXDI-55G, Canon, Japan) with dosimeter at tube voltage from 40-120 kV and 100 mA tube current. CT image data were acquired on a CT scan (Lightspeed, GE, USA) at 120 kV and 100 mA.
Results: These tissue equivalent materials had different μ (Fig.1). The CT numbers at 120 kV of these materials were also different, ranging from -42-630 HU (Table1). CT number of ABS was negative value, indicating that X-ray attenuation of ABS was weaker than that of water. Other materials had positive CT numbers and stronger X-ray attenuation than water. Several factors affect X-ray attenuation. Some are related to the x-ray beam and the others to properties of the material. The properties of material include the density (ρ) and the effective atomic number (Zeff). In general, substance with higher Zeff or ρ will absorb more X-rays, resulting in more X-ray attenuation.
Conclusion: These results would make us more familiar with tissue equivalent materials, as well as providing clear guidance in selecting materials suitable as real tissue.
Not Applicable / None Entered.
Not Applicable / None Entered.