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State-Of-The-Art in MRI-Guided Radiotherapy

C Glide-Hurst1*, P Liu2*, D Ma3*, N Mickevicius4*, M Kim5*, M Boss6*, (1) University of Wisconsin, Madison, WI, (2) The University of Sydney, Eveleigh, ,(3) Case Western Reserve, ,,(4) ,Madison, WI, (5) University Of Michigan, ,,(6) American College of Radiology, Philadelphia, PA

Presentations

3:30 PM Introduction to the State-of-the-art in MRI-guided Radiotherapy - C Glide-Hurst, Presenting Author
3:40 PM Next-generation Target Tracking Using MRI Guidance - P Liu, Presenting Author
3:58 PM MRI Fingerprinting - D Ma, Presenting Author
4:16 PM Challenges and Solutions for Quantitative Imaging on Low-Field MR-Guided RT Systems - N Mickevicius, Presenting Author
4:34 PM Toward Patient-Specific Radiotherapy: Biologically Informed Tumor Targeting in Glioblastoma - M Kim, Presenting Author
4:52 PM Standards to Reduce Variability in Quantitative MRI - M Boss, Presenting Author
5:10 PM Panel Discussion - N Mickevicius, Presenting Author

SU-EF-TRACK 4-0 (Sunday, 7/25/2021) 3:30 PM - 5:30 PM [Eastern Time (GMT-4)]

Magnetic resonance imaging (MRI) is playing an increasingly large role in the treatment of cancer with radiation therapy. With applications ranging from biologically informed treatment planning to in-room motion management, MRI is a versatile tool with far-reaching advantages. This session covers several cutting-edge MRI methods and their application to radiation therapy planning and delivery. The first talk will cover the use of real-time MR guidance for tumor tracking for multiple targets in the presence of patient motion. Quantitative MRI metrics are rapidly being adopted as imaging biomarker surrogates for tumors and organs at risk. One approach, magnetic resonance fingerprinting, will be described as a state-of-the-art method for rapid quantitative MRI. Next, a presentation will be given on overcoming the challenges of quantitative imaging on low field MRI-guided radiation therapy systems. To ensure rigor and reproducibility in quantitative MRI, a presentation on standards to reduce variability will be given. Finally, a talk on the novel use of MRI for patient specific radiation therapy treatment planning for high-grade brain tumors in a clinical trial will be presented by a physician.

Learning Objectives:
1. Describe real-time multi-target tracking on an MRI-guided radiation therapy system.
2. Understand the concept of magnetic resonance fingerprinting for rapid quantitative MRI.
3. Describe the challenges of quantitative imaging on low field strength MRI scanners.
4. Describe standards to reduce variability in quantitative imaging.
5. Introduce methods for patient-specific treatment of glioblastoma tumors in a clinical trial.

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