H Huang*, X Duan, A Howansky, J Stavro, A Goldan, A Lubinsky, W Zhao, SUNY Stony Brook, Stony Brook, NY

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  H Huang

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SU-IePD-TRACK 2-2 (Sunday, 7/25/2021) 3:00 PM - 3:30 PM [Eastern Time (GMT-4)]

Purpose: Dual-energy (DE) contrast-enhanced (CE) breast imaging requires registered low energy (LE) and high energy (HE) images for DE subtraction and is susceptible to patient motion. The motion artifacts could be more severe for CE digital breast tomosynthesis. Dual-layer (DL) detectors allow acquisition of LE and HE images in one x-ray exposure which minimizes patient motion. We aim to investigate a DL detector design for DE CE breast imaging and evaluate the impact of the thickness of x-ray filter and detector layer on the iodine detectability.

Methods: The DL detector consists of a top layer (TL) of amorphous selenium to generate the LE images and a bottom layer (BL) of columnar cesium iodine for the HE images with a glass substrate in between. The x-ray spectrum was simulated using tungsten target and rhodium (Rh) filter at 49 kVp with intensity that leads to a total radiation dose of 1.5 mGy to a 4-cm breast with 50% density. We calculated the x-ray spectrum for photons interacted in the TL and the BL for different Rh filter and TL thicknesses. The image signal was determined based on the x-ray energy deposition in the TL and BL and included quantum noise. We calculated the signal-difference-to-noise-ratio (SDNR) for 1 mg/cm² iodine in the DE-subtracted image and evaluated the tube-current time product (mAs) for different Rh filter thicknesses.

Results: Increasing the Rh filter thickness improves the spectral separation in the TL and BL and increases the iodine SDNR. Decreasing the TL thickness reduces the HE photon interactions in the TL and further increases the iodine SDNR. Rh filter with 200 um thickness achieves the highest iodine SDNR with practical mAs.

Conclusion: The proposed dual-layer detector is feasible for DE CE breast imaging to minimize patient motion.

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