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Keywords: Protons
MO-AB-TRACK 5-0New Developments in Flash RT
S Krishnan1*, P Montay-gruel2*, M Kim3*, C Desrosiers4*, A Mascia5*, (1) MD Anderson Cancer Center, Houston, TX, (2) Uc Irvine Health, (3) University of Pennsylvania, Philadelphia, PA, (4) University Hospital, Zionsville, IN, (5) University of Cincinnati Medical Center, Cincinnati, OH
MO-IePD-TRACK 1-3A Novel Integrating Proton Radiography System with a Monolithic Scintillator Detector
C Darne1*, D Robertson2, F Alsanea3, I Tendler4, L Perles5, C Collins-Fekete6, S Beddar7, (1) UT MD Anderson Cancer Center, Houston, TX, (2) Mayo Clinic Arizona, Phoenix, AZ, (3) UT MD Anderson Cancer Center, Houston, TX, (4) UT MD Anderson Cancer Center, Houston, TX, (5) UT MD Anderson Cancer Center, Houston, TX, (6) University College London, London, GB, (7) UT MD Anderson Cancer Center, Houston, TX
MO-IePD-TRACK 6-1Quantifying of the Afterglow Effect From a Chromium-Doped Alumina Scintillator Following Proton Irradiation
T Geoghegan1*, K Patwardhan1, B Smith1, R Flynn1, J Yu2, A Gutierrez2, D Hyer1, (1) University of Iowa Hospital and Clinics, Iowa City, IA, (2) Miami Cancer Institute, Baptist Health South Florida, Miami, FL
PO-GePV-M-63The Effects of Compton Camera Data Acquisition Timing and Readout On Prompt Gamma Images Acquired at Clinical Proton Beam Dose Rates
J Polf1*, P Maggi1, R Panthi2, D Mackin3, S Peterson4, S Beddar3, (1) University of Maryland School of Medicine, Baltimore, MD, (2) Rush University Medical Center, Chicago, IL, (3) MD Anderson Cancer Center, Houston, TX, (4) University of Cape Town, Rondebosch, ,ZA
PO-GePV-M-86Comparison of Online Adaptation and Offline Re-Planning for Head and Neck Intensity-Modulated Proton Therapy
M Bobic1,2*, A Lalonde1, K Nesteruk1, H Lee1, J Verburg1, G Sharp1, B Winey1, A Lomax2,3, H Paganetti1, (1) Massachusetts General Hospital and Harvard Medical School, Boston, MA, (2) ETH Zurich, Zurich, CH, (3) Paul Scherrer Institute, Villigen, CH
PO-GePV-M-222Direct Proton Dosimetry for Fractionated Radiotherapy: Dose Invariance Features and Mono-Endpoints
K Wang1*, R Beatty2, (1) UPMC Hillman Cancer Center, Pittsburgh, PA, (2) M.S. Hershey Medical Center, Hershey, PA
PO-GePV-P-26First Quality Assurance Implementation of Treatment Planning System for Pencil Beam Scanning Proton Radiotherapy
W Xiong*, G Yu, M Kang, S Huang, H Lin, New York Proton Center, New York, NY
PO-GePV-T-694D Treatment Planning for Lung Proton Therapy: Treatment Design and Evaluation
V T Taasti*, D Hattu, F Vaassen, R Canters, M Velders, J Mannens, J van Loon, I Rinaldi, M Unipan, W van Elmpt, Department of Radiation Oncology (MAASTRO), GROW - School for Oncology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
PO-GePV-T-71Radiobiological Evaluation of Physical Metrics in IMPT and VMAT Planning for Prostate Cancer Patient with Metal Hip Prostheses
W Hsi1*, T Lee2, (1) Univerisity Florida Health Proton Therapy Institute, Jacksonville, Florida, (2) Indiana University Health Arnett, Lafayette, IN
PO-GePV-T-72Developing a Workflow Using Supercomputer Accelerated Monte Carlo Simulation Based On Machine Log-Files for Patient Specific Quality Assurance of the Mevion S250i Proton Therapy System
B Chiang*, Y Chen, S Ahmad, University of Oklahoma Health Sciences Center, Oklahoma City, OK
PO-GePV-T-76Open Source TPS for Bragg Peak Proton FLASH Treatment Plans
L Hotoiu1*, A Pin2, S Deffet3, E Sterpin3,4, R Labarbe5, (1) Ion Beam Applications SA, Louvain-la-neuve, WBR, BE, (2) Ion Beam Applications Sa, Louvain-la-neuve, WBR, BE, (3) Universite catholique de Louvain, Molecular Imaging Radiotherapy and Oncology MIRO, Louvain-la-Neuve, BE, (4) KULeuven, Laboratory of Experimental Radiotherapy Department of Oncology Faculty of Medicine, Leuven, BE, (5) Ion Beam Applications (IBA), Louvain-la-neuve, WBR, BE
PO-GePV-T-77Virtual Particle Monte Carlo (VPMC), a New Concept to Avoid Simulating Secondary Particles in Proton Therapy Dose Calculation
J Shan*, M Fatyga, W Liu, Mayo Clinic Arizona, Phoenix, AZ
PO-GePV-T-78Experimental Validation of Clinical Proton Dose Calculation Algorithms for Breast Prostheses and Tissue Expanders
C Chen*, P Tsai, S Huang, JI Choi, H Lin, New York Proton Center, New York, NY
PO-GePV-T-79Development of a Fast and Memory-Efficient Monte Carlo Code for Proton Dose Calculation
H Lee*, J Shin, J Verburg, H Paganetti, Massachusetts General Hospital, Boston, MA
PO-GePV-T-80Three-Dimensional Dose and LETd Prediction in Proton Therapy Using Artificial Neural Networks
F Pirlepesov*, V Moskvin, L Wilson, A Breuer, T Merchant, A Faught, St. Jude Children's Research Hospital, Memphis, TN
PO-GePV-T-82Determination of Plan Deliverability and Treatment Time Estimation for Proton Pencil Beam Therapy Using a Machine Emulator Script
S Mossahebi1*, E Makdsay Hana1, J Williams1, B Algawwam1, A Meijers2, B Yi1, (1) University of Maryland Medical School, Baltimore, MD, (2) Varian Medical Systems, Palo Alto, CA
PO-GePV-T-83Characterizing the Entrance Dose Induced by a Dynamic Collimation System for Pencil Beam Scanning Proton Therapy Using a Commercial Multilayer Ionization Chamber
N Nelson1*, W Culberson1, B Smith2, R Flynn2, D Hyer2, P Hill3, (1) University of Wisconsin-Madison, School of Medicine and Public Health, Department of Medical Physics, Madison, WI, (2) University of Iowa, Department of Radiation Oncology, Iowa City, IA, (3) University of Wisconsin-Madison, School of Medicine and Public Health, Department of Human Oncology, Madison, WI, USA
PO-GePV-T-84Log File-Based Patient Specific Quality Assurance: 5 Years of Experience in Pencil Beam Scanning Pediatric Proton Therapy
O Ates*, F Pirlepesov, C Hua, T E Merchant, L Zhao, St. Jude Children's Research Hospital, Memphis, TN
PO-GePV-T-85Feasibility of Delivering Exchanged PBS Treatment Plans in Two Gantries of Multiroom Proton Therapy System
C Fang1, Y Huang1,2,4*, T Yang3, L Cao1, G Zhang4, B Qu3, Z Wang1, Y Zhang4, S Xu1,3,4, (1) Hebei Yizhou Cancer Hospital, Zhuozhou, Hebei, CN, (2) The Hong Kong Polytechnic University, Kowloon, Kowloon, HK, (3) Chinese PLA General Hospital, Beijing, Beijing, CN, (4) Beihang University, Beijing, Beijing, CN
PO-GePV-T-87Radiation Therapy Interference with Cardiovascular Implantable Electronic Devices; Comparison of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy
A Anvari*, T Alfonzetti, A Butala, M Carpenter, A Kassaee, I Paydar, J Jones, D Mihailidis, University of Pennsylvania, Philadelphia, PA
PO-GePV-T-89Clinical Evaluation of Optically Stimulated Luminescence Dosimeters Dose Accuracy in Intensity Modulated Proton Therapy
J Yu*, A Wroe, A Gutierrez, Miami Cancer Institute, Baptist Health South Florida, Miami, FL
PO-GePV-T-90Influence of Beam Quality Correction Factors On Measurement Depth in Scanning Proton Beams Using Monte Carlo Calculation
M Ichihara1*, K Yasui2, C Omachi3, T Toshito3, J Nagata1, R Oshika1, S Kurata1, N Hayashi2,(1) Graduate school of Health Sciences, Fujita Health University, Toyoake, Aichi, JP, (2) School of Medical Science, Fujita Health University, Tayoake, Aichi, JP, (3)Nagoya Proton Therapy Center, Nagoya, Aichi, JP
PO-GePV-T-93Can An Ionization-Chamber Array Be Used for QA of Proton SBRT Beams?
A Stanforth1*, Z Diamond1, P Sabouri2, M Zhu1, J Zhou1, R Slopsema1, (1) Emory University, Atlanta, GA, (2) Miami Cancer Institute, Miami, FL,
PO-GePV-T-94Novel Collimator for High-Throughput Proton FLASH-RT Murine Hemithorax Irradiations
S Mossahebi, Y Poirier*, A Gerry, C Repetto, Z Vujaskovic, I Jackson, A Sawant, University of Maryland School of Medicine, Baltimore, MD
PO-GePV-T-97Optimizing Design And commissioning of a Synchrotron Proton Beamline for FLASH Preclinical experiments
U Titt1*, M Yang1, X Wang1, S Lin1, X Zhu1, K Iga2, N Sahoo1, A Koong1, X Zhang1, R Mohan1, (1) MD Anderson Cancer Center, Houston, TX, (2) Hitachi America, Ltd.
PO-GePV-T-106Dose to Cardiac Implantable Electronic Devices in Patients Receiving Proton Beam Therapy
T Alfonzetti*, A Anvari, A Butala, M Carpenter, A Kassaee, I Paydar, J Jones, D Mihailidis, University of Pennsylvania, Philadelphia, PA
PO-GePV-T-107Dosimetric Comparison for Unfavorable Early Stage Lung Cancer: Intensity Modulated Proton Therapy Versus Volumetric Arc Photon Therapy
S O'Reilly*, P Singh, B Hartl, E Diffenderfer, K Cengel, W Levin, A Berman, S Feigenberg, University of Pennsylvania, Philadelphia, PA
PO-GePV-T-109Dosimetric Comparison of Pencil Beam Scanning Proton Plans with Different Aperture Modes
Y Yuan1*, D DeBlois1, Y Chen1, C Frame1, D Pang1, (1) Department of Radiation Medicine, MedStar Georgetown University Hospital, Washington DC, DC
PO-GePV-T-110Systematic Study of Penumbra Reduction with Adaptive Aperture for Hyperscan Spot Scanning Proton Beams
Y Chen*, C Frame, Y Yuan, T Ma, D Pang, MedStar Georgetown University Hospital, Washington, DC
PO-GePV-T-114Initial Experience with a Head and Neck RapidPlan Model for Pencil Beam Scanning Proton Therapy
K McConnell*, J Snider, J Nemec, R Cardan, UAB University of Alabama, Birmingham, Birmingham, AL
PO-GePV-T-115Should We Be Considering Biological Robustness in Proton Therapy?
A Faught*, L Wilson, M Gargone, F Pirlepesov, V Moskvin, C Hua, St. Jude Children's Research Hospital, Memphis, TN
PO-GePV-T-116Assessment of A Knowledge-Based Planning for Robustly-Optimized Intensity Modulated Proton Therapy for Head and Neck Cancer
Y Xu*, M De Ornelas, J Cyriac, E Bossart, K Padgett, M Butkus, T Diwanji, M Samuels, N Dogan, University of Miami, Miami, FL
PO-GePV-T-117Knowledge-Based Planning for Robustly-Optimized Intensity Modulated Proton Therapy of Prostate Cancer
Y Xu1*, N Brovold2, E Bossart1, K Padgett1, M Butkus1, T Diwanji1, A King1, A Dal Pra1, M Abramowitz1, A Pollack1, N Dogan1, (1) University of Miami, Miami, FL (2) Henry Ford Health System, Southfield, MI
PO-GePV-T-118Assess the Interplay Effect Based On the Cyclotron Accelerator Proton Therapy System Machine-Specific Delivery Sequence Model
L Zhao1*, G Liu1, J Shen2, A Lee3, D Yan1, R Deraniyagala1, C Stevens1, W Zheng1, X Li1, S Tang3, X Ding1, (1) Beaumont Health System, Royal Oak, MI, (2) Mayo Clinic, Phoenix, AZ, (3) US Oncology, Coppell, TX
PO-GePV-T-119Determination of Virtual Source Points for Mevion S250i Pencil Beam Scanning Proton System
Y Chen*, C Frame, T Ma, Y Yuan, D Pang, MedStar Georgetown University Hospital, Washington, DC
PO-GePV-T-120Effects of the Activated Dental Metal Induced by Proton Beam Irradiation for Head and Neck Cancer: A Phantom Study
R Kato1*, T Kato1, 2, T Sagara1, Y Narita1, K Takayama1, M Murakami1, (1) Southern Tohoku Proton Therapy Center, (2) Fukushima Medical University
PO-GePV-T-128Dynamically Collimated Spatially Fractionated (GRID) Pencil Beam Scanning Proton Therapy
B Smith*, B Allen, D Hyer, University of Iowa, Iowa City, IA
PO-GePV-T-129Impact of Noise Level On the Analysis of Proton Exposed Targets
F Saheli1*, N Vosoughi2, Z Riazi3, H Shahabinejad4, F Rasouli5, (1) Sharif, Tehran, IR, (2) (3) (4) (5)
PO-GePV-T-132Preliminary Investigation of the Dosimetric Impact of Common Dental Restorative Materials On Proton Beams
A Gomez1*, M Leyva2, L Coutinho1, E B Rosen1, N Kalman1, M Hobson1, (1) Miami Cancer Institute, Baptist Health South Florida, Miami, FL, (2)Provision Cares Proton Therapy Center,Knoxville, TN,
PO-GePV-T-133Wireless Device for Adaptive Planning Based Upon Thermoacoustic Range Estimates - Design and Benchtop Validation
S Patch1*, M Narayanaswamy2, (1) UW-Milwaukee, Milwaukee, WI, (2) Swamy Enterprises,
PO-GePV-T-134Sensitivity of Target Coverage and Patient Specific IMPT QA to Spot Positioning Errors
S Mossahebi1*, P Sabouri2, B Zhang1, E Makdsay Hana1, J Williams1, S Chen1, (1) University of Maryland Medical School, Baltimore, MD, (2) Miami Cancer Institute, Miami, FL
PO-GePV-T-135Impact of Spot Position Uncertainties On Intensity Modulated Proton Therapy Plans for Head and Neck Cancers
P Sabouri1*, S Mossahebi2, B Zhang2, S Chen2, (1) Miami Cancer Institute, Miami, FL, (2) University of Maryland Medical School, Baltimore, MD
PO-GePV-T-136Impact of Esophageal and Biliary Stents On Proton Dose Calculation
S Mossahebi1*, P Sabouri2, G Kim1, J Polf1, J Molitoris1, B Greenwald1, P Darwin1, S Chen1, (1) University of Maryland Medical School, Baltimore, MD, (2) Miami Cancer Institute, Miami, FL
PO-GePV-T-138The Benefit of Novel Beam Arrangements Made Feasible by Range Uncertainty Reductions in Proton Therapy for Brain and Skull Base Tumors
S Tattenberg1,2*, T Madden2, B Gorissen3, T Bortfeld2, K Parodi1, J Verburg2, (1) Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universitaet Muenchen, Garching, Germany (2) Division of Radiation Biophysics, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA (3) Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA
PO-GePV-T-323Dosimetric Impact of Materials Override of Hydrogel Spacer in Stereotactic Body Proton Therapy (SBPT) for Locally Advanced Pancreas Cancer (LAPC)
D Han1*, H Hooshangnejad 2, W Yao3, J Jatczak4, K Ding5, (1) University of Maryland, Baltimore, MD, (2) Johns Hopkins University, School of Medicine, Biomedical Engineering, Baltimore, MD, (3) University of Maryland School of Medicine, Baltimore, MD, (4) University Of Maryland, ,,(5) Johns Hopkins University, Baltimore, MD
PO-GePV-T-417Appropriate Modality for Salvage Radiation Therapy for Local Failure After Primary Lung SBRT
T Arsenault*, K Lyons, A Gross, T Biswas, M Yao, N Azar, C Towe, T Podder, University Hospitals Cleveland Medical Center, Cleveland, OH
SU-D-TRACK 6-6The Utility of Medical Physics Proton Peer Review for Clinical Trials
P Taylor*, J Lowenstein, D Followill, S Kry, UT MD Anderson Cancer Center, Houston, TX
SU-IePD-TRACK 5-7Proton Arc Therapy as An Alternative to Syed Interstitial High Dose Rate (HDR) Brachytherapy for Treating a Gynecological Cancer Patient with Lateral Disease Extension
B Yi*, S Mossahebi, E Nichols, M Guerrero, N Lamichhane, P Mohindra University of Maryland School of Medicine, Baltimore, MD
SU-IePD-TRACK 6-2Experimental Verification of Scanning Magnet with Distributed Winding Coils for Particle Beam Therapy
K Nagashima*, T Yamada, T Nomura, S Soeda, Hitachi, Ltd.
TH-C-TRACK 6-3Hypersensitivity of Cancer Cells to Photon and Proton Radiation Caused by Disruption of Cell Cycle Arrest by An ATR Inhibitor
M Manandhar*, S Bright, B Turner, D Flint, M Ben Kacem, D Martinus, S Shaitelman, G Sawakuchi, University of Texas MD Anderson Cancer Center, Houston, TX
TH-D-TRACK 5-1A Direct Machine-Specific Parameters Incorporated Spot-Scanning Proton Arc (SPArc) Algorithm
G Liu1,2*, L Zhao1, D Yan1,X Li1, X Ding1, (1) Beaumont Health System, Royal Oak, MI,USA (2) Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan,China
TU-B-TRACK 6-2Model-Based Reconstruction for Proton CT Detected with Multiple-Layer Ionization Chamber
X Chen*, B Sun, Y Hao, F Reynoso, A Darafsheh, D Yang, T Zhang, T Zhao, Washington University School of Medicine, St. Louis, MO
TU-B-TRACK 6-3Neural Network Based Event Classification to Improve Compton Imaging for Proton Beam Range Verification
C Barajas1, G Kroiz1, J Polf2*, S Peterson3, D Mackin4, S Beddar4, M Gobbert1, (1) University Of Maryland, Baltimore County, (2) University of Maryland School of Medicine, Baltimore, MD, (3) University of Cape Town, Rondebosch, ,ZA, (4) UT MD Anderson Cancer Center, Houston, TX
TU-B-TRACK 6-4Performance Evaluation of An Optimization Method for Fluence-Modulated Proton CT with Dose and Variance Objectives
J Dickmann1, F Kamp2, M Hillbrand3, S Corradini4, C Belka5, R Schulte6, K Parodi7, G Dedes8, G Landry9*, (1) Ludwig-Maximilians-Universitat Munchen, Garching Bei Munchen, BY, DE, (2) Cologne, NW, (3) Kantonsspital Graubunden,(4) University Hospital, Lmu Munich,(5) No institution provided,(6) Loma Linda University, Loma Linda, CA, (7) Ludwig-Maximilians-Universitat Munchen, Garching B. Munich, (8) Ludwig-Maximilians-Universitat Munchen, Munich, DE, (9) Ludwig-Maximilians-Universitat Munchen, Munich, DE
TU-B-TRACK 6-5Scatter Correction of 4D Cone Beam Computed Tomography for Time-Resolved Proton Dose Calculation: Porcine Lung Phantom Validation
H Schmitz1*, M Rabe1, G Janssens2, J Dinkel3, S Rit4, K Parodi5, C Belka1,6, C Kurz1,5, F Kamp1,7, G Landry1,5, (1) Department of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany, (2) Ion Beam Applications SA, Louvain-la-neuve, Belgium, (3) Department of Radiology, University Hospital, LMU Munich, Munich, Germany, (4) Centre Leon Berard, Universite de Lyon, Lyon, France, (5) Department of Medical Physics, Ludwig-Maximilians-Universitaet Muenchen (LMU Munich), Garching (Munich), Germany, (6) German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany, (7) Department of Radiation Oncology, University Hospital Cologne, Cologne, Germany
TU-B-TRACK 6-7Beam Path Length From Isocenter to Skin On Cone Beam CT Images as An Adaptive Planning Indicator of Head and Neck Patients Undergoing Proton Therapy
N Biswal*, B Zhang, J Molitoris, M Witek, B Yi, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD
TU-C-TRACK 4-7Protons Combined with PARP Inhibition Sensitize Cancer Cells and Activate Immune Signaling More Than Photons
M Ben Kacem*, S Bright, B Turner, D Flint, M Manandhar, D Martinus, C McFadden, S Shaitelman, G Sawakuchi, University of Texas MD Anderson Cancer Center, Houston, TX
TU-C-TRACK 6-2DNA Repair Inhibitors Combined with Protons Increase Cell Radiosensitivity in Vitro
D Flint*, S Bright, B Turner, M Manandhar, M Ben Kacem, S Shaitelman, G Sawakuchi, UT MD Anderson Cancer Center, Houston, TX
TU-D-TRACK 6-1ATR Inhibition Suppresses DNA Damage Signaling and Sensitizes Cancer Cells to Photons and Protons
D Martinus*, S Bright, D Flint, B Turner, M Manandhar, M Ben Kacem, S Shaitelman, G Sawakuchi, UT MD Anderson Cancer Center, Houston, TX
TU-E-TRACK 5-2Analysis of Proton Inter-Track Interactions at Ultra-High Dose Rates
S Thompson*, K Prise, S McMahon, Queen's University Belfast, Belfast, GB
TU-E-TRACK 5-3BEST IN PHYSICS (THERAPY): FLASH Sparing of Normal Tissue in a Proton Spread Out Bragg Peak
M Kim*, I Verginadis, A Haertter, D Goia, K Shoniyozov, J Zou, C Koumenis, J Metz, K Cengel, L Dong, E Diffenderfer, University of Pennsylvania, Philadelphia, PA
TU-E-TRACK 5-4Measuring Oxygen Concentration at Ultra-Fast Rates During Proton FLASH Delivery Using Phosphorescence Quenching of Soluble Oxyphor Probes
A L Van Slyke*, M El Khatib, K Shoniyozov, E Diffenderfer, M Kim, C J Koch, S A Vinogradov, R D Wiersma, University of Pennsylvania, Philadelphia, PA
TU-EF-TRACK 4-8Thermoacoustic Range Verification During Pencil Beam Delivery of a Clinical Plan to An Abdominal Imaging Phantom 
S Patch1*, C Nguyen2, M Cohilis3, K Souris4, J Lambert5, S Ono6, T Lynch7, G Janssens8, R Labarbe9, (1) UW-Milwaukee, Milwaukee, WI, (2) Uw-milwaukee, ,,(3) University catholique de Louvain, Bruxelles, ,BE, (4) UCL, Brussels, ,BE, (5) The Rutherford Cancer Centres, ,,(6) Computerized Imaging Reference Systems, Inc, ,,(7) CIRS, Norfolk, VA, (8) Ion Beam Applications SA, Louvain-la-neuve, ,BE, (9) Ion Beam Applications (IBA), Louvain-la-neuve, ,BE
TU-F-TRACK 5-4Prompt Gamma Timing as a Real-Time Relative Dose Rate Monitor of FLASH Proton Delivery
A Haertter*, M Kim, J Zou, K Shoniyozov, S Avery, B Teo, J Metz, K Cengel, L Dong, E Diffenderfer, Hospital of the University of Pennsylvania; Department of Radiation Oncology, Philadelphia, PA. USA
TU-IePD-TRACK 5-1A Feasibility Study of Proton Beam Dosimetry Using Cerenkov Radiation
S Thompson*, University of Florida, Gainesville, FL
TU-IePD-TRACK 5-2Characteristics Evaluation of Contact Lens in Vivo Ocular Dosimeter for Proton Therapy
J Son1*, J Han2, J Jeong3, S Jung3, C Choi1, J Park1, J Kim1, (1) Department of Radiation Oncology, Seoul National University Hospital, Seoul, KR, (2) Biomedical Research Institute, Seoul National University Hospital, Seoul, KR,(3) Proton therapy center, National Cancer Center, Goyang-si Gyeonggi-do, KR,
TU-IePD-TRACK 5-24D Robust Optimization in Small Spot Intensity-Modulated Proton Therapy (IMPT) for Distal Esophageal Carcinoma
H Feng*, J Shan, J Ashman, W Rule, R Bhangoo, N Yu, J Chiang, M Fatyga, W Wong, S Schild, T Sio, W Liu, Mayo Clinic Arizona, Phoenix, AZ
TU-IePD-TRACK 5-4A Novel Component Method to Delineate Surgical Spine Implants for Proton Monte Carlo Dose Calculation
C Chang1, S Charyyev2, J Harms3, R Slopsema4, J Wolf5, D Refai6, T Yoon7, M McDonald8, J Bradley9, S Leng10, J Zhou11, X Yang12, L Lin13*, (1) Emory University, Alpharetta, GA, (2) Emory University, Atlanta, GA, (3) Emory University, Atlanta, GA, (4) Emory University, Atlanta, GA, (5) Emory University, Atlanta, GA, (6) Emory University, Atlanta, GA, (7) Emory University, Atlanta, GA, (8)Emory University, Atlanta, GA, (9) Emory University School Of Medicine, ,,(10) Mayo Clinic, Rochester, MN, (11) Emory University, Atlanta, GA, (12) Emory University, Atlanta, GA, (13) Emory University, Atlanta, GA
TU-IePD-TRACK 5-4Proton Modulation Technique But Not Acceleration Method Is Associated with Variations in Dose-Averaged Linear Energy Transfer
L Wilson*, V Moskvin, F Pirlepesov, A Faught, St. Jude Children's Research Hospital, Memphis, TN
TU-IePD-TRACK 5-5Investigate the Delivery Efficiency and Accuracy of Spot-Scanning Proton Arc (SPArc) in Comparison with Conventional IMPT, Automatic Step-And-Shoot Multifield IMPT
L Zhao*, G Liu, D Yan, X Li, X Ding, Beaumont Health System, Royal Oak, Michigan
TU-IePD-TRACK 5-7A 3D Printed Phantom for Range Verification of Low-Energy Proton Fields
G Roe1*, J Scholey2, S St. James2, (1) University Of California-Davis, Davis, CA (2) University of California San Francisco, San Francisco, CA
WE-A-TRACK 6-2Dose-Averaged LET in Proton Therapy for Patients with MRI Abnormalities and Its Role in Normal Tissue Complication Probability
A Bertolet1*, R Abolfath2, D Carlson3, R Lustig3, C Hill-Kayser3, M Alonso-Basanta3, A Carabe-Fernandez4, (1) Massachusetts General Hospital and Harvard Medical School, Boston, MA, (2) New Jersey Urology, West Orange, NJ, (3) University of Pennsylvania, Philadelphia, PA, (4) Hampton University Proton Therapy Institute, Hampton, VA
WE-A-TRACK 6-3Robust Optimization of Proton Therapy Treatments Using a Variable Range Uncertainty
M Cohilis1*, E Sterpin1,2, C Chang3, S Rivas1, L Lin4, J Lee1, K Souris1, (1) UCLouvain, Brussels, BE, (2) KU Leuven, Leuven, BE (3) Emory University, Alpharetta, GA (4) Emory Proton Therapy Center, Atlanta, GA
WE-A-TRACK 6-4The Effect of Treatment Planning Approach On Head-And-Neck IMPT for Patients with Implanted Dental Fixtures
Y Hu1*, O Muller2, R Foote1, D Mundy1, (1) Mayo Clinic, Department of Radiation Oncology, Rochester, MN, USA(2) Mayo Clinic, Department of Advanced Prosthodontics, Rochester, MN, USA
WE-A-TRACK 6-6A Beamlet-Based Optimization Algorithm for Arc Proton Therapy Planning
S Wuyckens1*, G Janssens2, E Sterpin1,3, J Lee1, K Souris1, (1) UCLouvain, Molecular Imaging, Radiotherapy and Oncology (MIRO), Brussels, BE, (2) Ion Beam Applications SA, Louvain-la-neuve, BE, (3) KULeuven, Oncology Department, Leuven, BE
WE-A-TRACK 6-7The Combined Effects of Protons and An Inhibitor of ATR Increase Micronuclei Formation and Potentiate Anti-Tumor Immunity
B Turner*, S Bright, D Flint, G Sawakuchi, S Shaitelman, M Manandhar, M Ben Kacem, D Martinus, University of Texas MD Anderson Cancer Center, Houston, TX
WE-B-TRACK 6-2The Potential of Online-Adaptive Head and Neck Proton Therapy to Reduce Normal Tissue Complication Probability
A Lalonde*, M Bobic, B Winey, J Verburg, G Sharp, H Paganetti, Massachusetts General Hospital / Harvard Medical School, Boston, MA
WE-B-TRACK 6-3Design and Initial Testing of An Isocenter Alignment Prototype for the Proton Dynamic Collimation System
T Geoghegan1*, K Patwardhan1, B Smith1, R Flynn1, J Yu2, A Gutierrez2, D Hyer1, (1) University of Iowa Hospital and Clinics, Iowa City, IA, (2) Miami Cancer Institute, Baptist Health South Florida, Miami, FL
WE-B-TRACK 6-5BEST IN PHYSICS (THERAPY): New System for Fast and Independent Proton Beam Energy Measurement
F Milian1,2*, O Villarreal1, M Abujami1, R Cirio1, C Galeone3, S Giordanengo3, N Minafra4, V Monaco1, E Verroi5, A Vignati2, R Sacchi1, (1) University of Torino, Physics Department, Turin, Italy, (2) State University of Santa Cruz, UESC, Ilheus, Brazil, (3) National Institute for Nuclear Physics INFN, Turin division, Turin, Italy, (4) University of Kansas, Lawrence, United States, (5) Trento Institute for Fundamental Physics and Applications, INFN, Povo, Italy
WE-IePD-TRACK 4-1IGRT-Based On-Line Dose Estimation in Proton Therapy
S Flampouri1*, W LePain2, M McDonald1, (1) Emory University, Atlanta, GA, (2) Georgia Tech, Atlanta, GA
WE-IePD-TRACK 4-2A Scatter-Rejection Method for Proton Computed Tomography
J Houri1*, A Kapadia2,3, (1) Duke University Medical Physics Graduate Program, Durham, NC, (2) Oak Ridge National Laboratory, Oak Ridge, TN, (3) Duke University Medical Center, Durham, NC
WE-IePD-TRACK 4-3Improving the Performance of a Proton Computed Tomography Scanner with An Empirical Artifact Correction Method
G Landry*6,7,1, J Dickmann1, C Sarosiek2, S Goetz1, M Pankuch3, G Coutrakon2, R P Johnson4, R W Schulte5, K Parodi1, G Dedes1, (1) Ludwig-Maximilians-Universitaet Muenchen, Munich, Germany, (2) Northern Illinois University, DeKalb, IL, (3) Northwestern Medicine Chicago Proton Center, Warrenville, IL, (4) U.C. Santa Cruz, Santa Cruz, CA, (5) Loma Linda University, Loma Linda, CA, (6) University Hospital, LMU Munich, Munich, Germany, (7) German Cancer Consortium (DKTK), Munich, Germany
WE-IePD-TRACK 4-4Assessment of Clinical to High Energy Proton Radiography Viability Using TOPAS
B Broder1*, M Freeman2, (1) University of Chicago, Chicago, IL, (2) Los Alamos National Laboratory, Los Alamos, NM
WE-IePD-TRACK 4-5Histogram Analysis Method of Water Equivalent Path Length to Evaluate Dose Variation Due to Anatomical Change in Spot-Scanning Proton Beam Therapy
T Fujii1*, S Takao2,3,4, T Matsuura2,3,4, S Hirayama1, N Miyamoto2,4, K Umegaki2,3,4, S Shimizu3,4,5, H Shirato6, (1) Hitachi Ltd., 1-1 7-chome, Omika-cho, Hitachi-shi, Ibaraki, JP,(2) Division of Quantum Science and Engineering, Faculty of Engineering, Hokkaido University, Sapporo, Hokkaido, JP,(3) Proton Beam Therapy Center, Hokkaido University Hospital, Sapporo, Hokkaido, JP,(4) Department of Medical Physics, Hokkaido University Hospital, Sapporo, Hokkaido, JP, (5) Department of Radiation Medical Science and Engineering, Faculty of Medicine, Hokkaido University, Sapporo, Hokkaido, JP, (6) Department of Proton Beam Therapy, Faculty of Medicine, Hokkaido University, Sapporo, Hokkaido, JP
WE-IePD-TRACK 4-6A Novel Reconstruction Method for 3D Cone Beam CT Images in Proton Therapy Using RTK
J Lindsay1*, A Bryce-atkinson1, M Taylor1,2, S Meara2,1, M Aznar1,2, M van Herk1,2, (1) The University of Manchester, Manchester, GB, (2) The Christie NHS Foundation Trust, Manchester, GB
WE-IePD-TRACK 4-7Performance of Dose Restoration in Head and Neck Cancer for Adaptive IMPT
E Borderias-Villarroel1*, V Taasti2, W Van Elmpt2, X Geets1,4, E Sterpin1,5, (1) MIRO-UCLouvain,Brussels,BE (2) Maastro Clinic, Maastricht, NL (3) Imagerie Moleculaire et Radiotherapie Experimental, Brussels,BE (4) KULeuven, Leuven, BE
WE-IePD-TRACK 5-1Development and Validation of a TOPAS Monte Carlo Model of a Dynamic Collimation System for Pencil Beam Scanning Proton Therapy
N Nelson1*, W Culberson1, D Hyer2, T Geoghegan2, K Patwardhan2, B Smith2, R Flynn2, J Yu3, S Rana3, A Gutierrez3, P Hill4, (1) University of Wisconsin-Madison, School of Medicine and Public Health, Department of Medical Physics, Madison, WI, (2) University of Iowa, Department of Radiation Oncology, Iowa City, IA, (3) Miami Cancer Institute, Department of Radiation Oncology, Miami, FL, (4) University of Wisconsin-Madison, School of Medicine and Public Health, Department of Human Oncology, Madison, WI, USA
WE-IePD-TRACK 5-3Influence of Sub-Lethal Damage Repair On Biological Effectiveness of Proton with the Consideration of Dose Delivery Time Structure in Scanning Proton Therapy
K Kasamatsu1*, H Hosoi2, S Tanaka3,4, K Miyazaki3, S Takao3,4, N Miyamoto3,4, K Umegaki3, T Hashimoto5, K Nishioka5, S Shimizu4,5, T Matsuura3,4, (1)Hokkaido University, Graduate School of Biomedical Science and Engineering, Sapporo, Japan (2)Hokkaido University, School of Engineering, Sapporo, Japan (3)Hokkaido University, Faculty of Engineering, Sapporo, Japan (4)Hokkaido University Hospital, Department of Medical Physics, Sapporo, Japan (5)Hokkaido University, Faculty of Medicine, Sapporo, Japan

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