Ballroom C
Purpose: Respiratory gated delivery with orthogonal real time cine MRI guidance is being developed on a 1.5T MR-Linac. To ensure dosimetry properties of gated beams remain the same as those of non-gated beams, this study reports, for the first time, a comprehensive dosimetry measurement of gated beams on the MR-Linac.
Methods: An investigational gating control software package was developed to interface to the service mode of the MR-Linac to trigger beam on and off. The package allowed to change intervals of beam-on and beam-off times with 0.01s increment. Using a Farmer type ion chamber (IC) and a 2D IC array dosimeter, the common dosimetry properties of the 7 FFF MV photon beams, including output, energy ratio, linearity and dose rate, tissue maximum ratios (TMR), and beam profiles, were measured under a variety of different gating conditions and beam settings, and compared with those measured under corresponding non-gated conditions. Spatial dose distributions for open and IMRT fields under different gated and non-gated conditions were also measured using a 3D diode detector array and IC and analyzed based on gamma criteria.
Results: The measurements of the machine outputs, energy ratio, linearity, and dose-rate, TMR, and profile under combinations of a wide range of beam-on [0.25s-20s] and beam-off times [0.5s-5s] agreed within 0.5% to those measured with the ungated beams. For example, the differences of the dosimetry properties between the commonly used respiratory gated conditions (beam on: 1s; beam off: 3s) and nongated conditions were within 0.4%. For the measurements of the open and IMRT fields with gated vs. nongated, the absolute point doses agreed within 0.7%, and all the 3D dose distributions achieved over 95% passing rates with clinically used gamma analysis criteria.
Conclusion: Respiratory gating does not alter beam dosimetry and can be safely and accurately delivered on the 1.5T MR-Linac.
Funding Support, Disclosures, and Conflict of Interest: Research partially funded by Elekta AB
Not Applicable / None Entered.
TH- External Beam- Photons: Motion management - intrafraction