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A Benchmark Study On BrachyVision ACUROS TPS in Modeling a Direction Modulated Brachytherapy Tandem Applicator

M Meftahi1*, W Song2, (1) Virginia CommonWealth University, Richmond, VA, (2) Virginia Commonwealth University, Henrico, VA

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PO-GePV-T-53 (Sunday, 7/10/2022)   [Eastern Time (GMT-4)]

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Purpose: A novel shielded tandem applicator for Direction Modulated Brachytherapy (DMBT) was introduced to improve the coverage of nonuniform targets in cervical cancer. This applicator has been recently modeled in BrachyVision (BV) TPS, a Model based Dose Calculation algorithm (MBDCA), for the clinical research. In this study, we aim to benchmark the accuracy of the TPS in modeling the DMBT tandem using Monte Carlo (MC) simulations.

Methods: The DMBT tandem applicator, made of an MR compatible tungsten alloy with six symmetrical grooves covered by a sheath of PEEK plastic, was simulated using GEANT4 MC simulation code. Subsequently, different scenarios were created using the BV TPS and reproduced by GEANT4 MC simulations, including the HDR source ‘at the center of water phantom’ and ‘at the middle of the DMBT applicator’ for the phantom with side length of 30 cm and 40 cm. An in-housed developed track length estimator was used to estimate dose inside the water phantoms and 2D/3D scoring were performed. Volumetric and 2D dose comparisons of TPS against MC results were further performed.

Results: there was better agreement between the TPS and MC results for the phantom with side length of 40 cm, such that 95% of the voxels were in the intervals [0% 8.5%] and [-6.5% 6.5%], for the source at the center of the water phantom and at the middle of the DMBT applicator, respectively. Nonetheless, there was good agreement (±3%) between TPS and MC results for both phantom sizes within 5 cm from the center of the HDR sources.

Conclusion: the results of this study indicated that there is a phantom size dependency for the TPS in the dose calculation, that could be due to scattering condition. Nevertheless, it seems the TPS could still provide good accuracy inside the area of clinical importance.

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