Y Wong¹*, H Chang², W Liu³, W Wang⁴, Y Zhang⁵, H Wu⁶, H Lee⁷, A Cheung⁸, T Li⁹, J Cai¹⁰, (1) The Hong Kong Polytechnic University, ,,(2) The University Of Hong Kong, ,,(3) ,,,(4) ,,,(5) Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing, 11, CN, (6) Beijing Cancer Hospital, Beijing, ,CN, (7) The University Of Hong Kong, ,,(8) ,,,(9) The Hong Kong Polytechnic University, Hong Kong, ,HK, (10) Hong Kong Polytechnic University, Hong Kong, ,CN

• 
  Y Wong

WE-C1000-IePD-F2-2 (Wednesday, 7/13/2022) 10:00 AM - 10:30 AM [Eastern Time (GMT-4)]

Exhibit Hall | Forum 2

Purpose: This study aims to propose a novel technique, Retrospective Motion Artifacts Suppression by Simulated radial K-space (R-MASSK), that can suppress motion artifacts and enhance image quality of clinically available 3D view-sharing 4D-MRI.

Methods: The R-MASSK technique was tested on clinically acquired 4D-MRI images of 20 liver cancer patients using 3D view-sharing sequences – TRICKS or TWIST, on a 1.5T or 3.0T scanners (10 patients for each scanner), respectively. The R-MASSK 4D-MRI, result-driven (RD) sorted 4D-MRI, RD sorted 4D-MRI followed by the sequential wavelet denoising (RD+D), and the original 4D-MRI were then quantitatively evaluated by signal-to-noise ratio (SNR), hepatic portal vein-to-liver parenchyma contrast-to-noise ratio (CNR), and gradient energy (GE) percentage decrease.

Results: The proposed R-MASSK technique shows significant improvement on motion artifacts and overall image quality in all three planes (coronal, sagittal, and axial), and all respiratory phases, as compared to the RD-sorted 4D-MRI and the original 4D-MRI. R-MASSK 4D-MRI shows higher SNR and CNR in all three planes as compared to the RD+D, RD, original 4D-MRI. For both cohorts of patients, the average magnitude of SNR (CNR) 22.7 ± 7.1 (16.6 ± 6.88), 15.0 ± 4.82 (10.82 ± 4.91), 14.4 ± 4.52 (10.4 ± 4.71), and 15.0 ± 4.8 (10.48 ± 4.91), respectively. The average magnitude of GE percentage decrease for R-MASSK 4D-MRI with respect to RD, RD+D, and original 4D-MRI are 29.6 % ± 12.4 %, 24.3 % ± 12.5 %, and 31.5 % ± 12.0 %, respectively.

Conclusion: Both qualitative and quantitative results suggest that R-MASSK technique is capable of suppressing motion artifacts and improving image quality in both axial, coronal, and sagittal planes of the 4D-MRI acquired by 3D view-sharing sequence.

Funding Support, Disclosures, and Conflict of Interest: This work is supported by funding from grants NIH R01 CA226899, GRF 15102118, HMRF 06173276

Keywords

MRI

Taxonomy

IM- MRI : 4D MRI

Contact Email