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Session: Imaging General ePoster Viewing [Return to Session]

Multimodal Image Translation Via Deep Learning Inference Model Trained in Video Domain

J Fan*, D Yang, J Wang, W Hu, Fudan University Shanghai Cancer CenterShanghaiCN


PO-GePV-I-63 (Sunday, 7/10/2022)   [Eastern Time (GMT-4)]

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Purpose: Current medical image translation is implemented in the image domain. Considering the medical image acquisition is essentially a temporally continuous process, we attempt to develop a deep-learning-based approach to solve the medical image translation problem in the video domain.

Methods: For a proof-of-concept demonstration, cone-beam computed tomography (CBCT) and computed tomography (CT) images from 100 patients were collected to demonstrate the feasibility and reliability of the proposed framework. A vid2vid framework based on the conditional GAN network, with carefully-designed generators, discriminators and a new spatio-temporal learning objective, was applied to realize the CBCT-CT image translation in the video domain. Four evaluation metrics, including mean absolute error (MAE), peak signal-to-noise ratio (PSNR), normalized cross-correlation (NCC), and structural similarity (SSIM), were calculated on all the real and synthetic CT images from 10 new testing patients to illustrate the model performance.

Results: The average values for all the evaluation metrics are 23.27 ± 5.53, 32.67 ± 1.98, 0.99 ± 0.0059, and 0.97 ± 0.028, respectively. Most of the pixel-wise hounsfield units (HU) value differences between real and synthetic CT images are within 50. The synthetic CT images have great agreement with the real CT images and the image quality is improved with lower noise and artifacts compared with CBCT images.

Conclusion: We developed a deep-learning-based approach to perform the medical image translation problem in the video domain. Although the feasibility and reliability of the proposed framework were demonstrated by CBCT-CT image translation, it can be easily extended to other types of medical images. The current results illustrate that it is a very promising method that may pave a new path for medical image translation research.


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