Purpose: 3D printing has been widely used in clinic and teaching. We have improved some tissue equivalent 3D printing materials for more intuitive, convenient and diversified applications in clinic and teaching.
Methods: Water was used as solvent, agarose, sodium chloride and pearl powder were used as solutes to make muscle tissue. Tumor tissue was prepared with water as solvent and agarose, sodium chloride and pearl powder as solute. For lung tissue, silica foam is composed of silica gel and curing agent. Then, silica gel was injected directly into the shell of lung tissue for 3D printing. CT scanning was used for tissue equivalence test, and antibacterial experiment was carried out.
Results: The modified materials were in close approximation to human tissues in terms of CT numbers. The antibacterial rate of E. coli was 54% higher than that of the blank control group.
Conclusion: 3D printing is simple and convenient. The improved tissue equivalent material is closer to real human tissue. According to clinical and teaching requirements, 3D anatomical model can be printed personalized for personalized dose verification.
Funding Support, Disclosures, and Conflict of Interest: This work was supported by Academic Promotion Program of Shandong First Medical University (2019QL009) Taishan Scholars Program of Shandong Province (TS201712065) Shandong medical and health science and technology development plan project(202009040454) Tai'an science and technology development plan project(2019NS156) Innovation and entrepreneurship training program (S202010439080) Innovation and entrepreneurship training program (202110439093)
3D, Phantoms, Tissue Equivalency